EDCs: The risk of exposure to low doses is underestimated

According to a report prepared jointly by the Endocrine Society and IPEN (International Pollutants Elimination Network) and published at the end of February, endocrine disruptors are more harmful to health globally than previously thought. Studies indicate that such substances pose a health risk even at low doses. Therefore, the limits that currently apply to EDCs do not reflect the state of scientific studies, the authors write.

Studies provide new insights

In fact, studies suggest that EDCs contribute significantly to diseases such as diabetes, inflammation, reproductive and neurological disorders, as well as being able to weaken the immune system. The report is based on studies of the following substances and substance classes, all of which are ubiquitous in the environment:

Glyphosate
Bisphenols and phthalates
Arsenic and inorganic lead
per- and polyfluorinated alkyl substances (PFAS)
brominated flame retardants

It has been observed that phthalates impede neurodevelopment, which manifests itself in impaired learning ability, attention disorders and impulsive behavior. Arsenic, on the other hand, promotes metabolic, cardiovascular and neurocognitive diseases and has been shown to inhibit reproductive function. PFAS are thought to interfere with the mode of action of oestrogen, testosterone and thyroid hormones.

The crux of animal testing

According to the lead author of the report, Andrea Gore, Professor of Neuroendocrinology at the University of Texas at Austin, animal studies are essential to understand the complex mechanisms of action. Ultimately, the endocrine system must be considered in the context of the body and the only way to do this is through animal studies.

If you have any questions, please do not hesitate to contact us at sales@kft.de.